Spatio-temporal correlation between topographic ERP mapping and positron emission tomography

Simultaneous measurement of PET excellent for spatial resolution and event-related potential (ERP) for temporal resolution was performed during the visual recognition task. Subjects were 12 normal adult males having given the informed consent. MRI was done for the morphological indicator of the PET results. PET was conducted by Shimadzu HEADTOME V after bolus injection of 15O-water to measure the cerebral blood flow (CBF). Electroencephalography was recorded simultaneously. The recognition task with the word, figure and human face was given during the measurements. At recognition of a famous person's face, ERP exhibited the negative peak around the occipital region after the latent time of 164 msec and PET exhibited the increased CBF in the gyruses of parahippocampus and fusiform, thus suggesting the correlation between electro-physiological activity and CBF change. (K.H.)