Published 1971
| Version v1
Journal article
The non-metabolite residue, a limitation to the tracer method
Creators
- 1. Princeton Univ., N.J. (USA)
- 2. Merck Sharp and Dohme Research Labs., Rahway, N.J. (USA)
Description
Abstract The occurrence of non‐metabolite residues from labeled drugs administered to animals is discussed. Selected are 14 C‐labeled thiabendazole, nitroglycerine, nortriptyline, amitryptiline, p ‐dime‐thylaminobenzene, nihydrazone and ronidazole. The rapid degradation which is responsible for the phenomenon requires that all tracer applications in living systems be accompanied by a demonstration of the biological stability of the parent compound.
Additional details
Identifiers
Publishing Information
- Journal Title
- Journal of Labelled Compounds
- Journal Volume
- 7
- Journal Issue
- 3
- Series
- J. Labelled Compd.
- Journal Page Range
- 225-232
- ISSN
- 0022-2135
INIS
- Country of Publication
- Belgium
- Country of Input or Organization
- Belgium
- INIS RN
- 3015763
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Resource subtype / Literary indicator
- No Abstract
- Descriptors DEI
- ANABOLISM; ANIMALS; CARBON 14; DECOMPOSITION; DRUGS; LABELLED COMPOUNDS; METHYL RADICALS; ORGANIC NITROGEN COMPOUNDS; RETENTION; TRACER TECHNIQUES
- Descriptors DEC
- METABOLISM
Optional Information
- Notes
- Updated automatically by Metadata and Full-Text Enrichment Agent