Clinical impact of Positron Emission Tomography (PET) on oncological patients and their potentially application context
Creators
Description
(PET) Positron Emission Tomography is a technique of nuclear medicine that has ability of detecting cancer through mechanisms based on molecular alterations of neoplastic processes. This review describes the PET Oncology applications and discusses the potential application of this technology in the sanitary and national academic framework . The most widely used in Oncology plotter is an analogue of laglucosa labelled with fluo: 18F-2-fluoro-2-Deoxy-D-glucose (FDG). In this way, the PET detects tumour retention of FDG, due to the highest glycolytic of cancer cells. In addition, the PET allow the study of the entire body at the same exploratory and some teams are coupled to systems of axial tomography (PET-CT). By ET-FDG, it is possible to diagnose, staging and restaged the majority of cancers, with diagnostic accuracy close to 90 per cent higher than the values provided by the conventional imaging techniques such. It is also possible to know early response to cancer treatments and obtain relevant medical prognosis information. (author)
Abstract (Spanish)
La tomografia de emision de positrones (PET) es una tecnica de medicina nuclear que tiene la capacidad de detectar el cancer por medio de mecanismos basados en las alteraciones moleculares de los procesos neoplasicos. En esta revision se describen las aplicaciones oncologicas del PET y se analiza la potencial aplicacion de esta tecnologia en el contexto sanitario y academico nacional. El trazador mas utilizado en oncologia es un analogo de laglucosa marcado con fluo: 18F-2-fluor-2-desoxi-D-glucosa (FDG). De esta forma, el PET detecta la retencion tumoral de FDG, debido al mayor indice glucolitico de las celulas cancerosas. Ademas, los tomografos PET permiten el estudio de todo el cuerpo en el mismo acto exploratorio y algunos equipos se encuentran acoplados a sistemas de tomografia axial computarizada (PET-TAC). Mediante ET-FDG es posible diagnosticar, estadificar y reestadificar la mayoria de los canceres, con exactitudes diagnosticas cercanas a 90 por ciento superior a los valores aportados por las tecnicas imagenologicas convencionales. Ademas, es posible conocer precozmente la respuesta a los tratamientos oncologicos y obtener informacion pronostica relevante. (author)Additional details
Additional titles
- Original title (Spanish)
- Impacto clinico de la tomografia de emision por positrones (PET) en pacientes oncologicos y su potencial aplicacion en el contexto sanitario y academico nacional
Publishing Information
- Journal Title
- Revista Medica del Uruguay (Montevideo. 1974)
- Journal Volume
- 22
- Journal Issue
- 3
- Journal Page Range
- p. 169-178
- ISSN
- 0303-3295
INIS
- Country of Publication
- Uruguay
- Country of Input or Organization
- Uruguay
- INIS RN
- 42064891
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ACCURACY; DIAGNOSIS; FLUORINE 18; GLUCOSE; NEOPLASMS; NUCLEAR MEDICINE; PATIENTS; PLOTTERS; POSITRON COMPUTED TOMOGRAPHY
- Descriptors DEC
- ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOHYDRATES; COMPUTER OUTPUT DEVICES; COMPUTER-GRAPHICS DEVICES; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HEXOSES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MEDICINE; MONOSACCHARIDES; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; SACCHARIDES; TOMOGRAPHY