Published August 2021
| Version v1
Journal article
Evaluation of indirect damage and damage saturation effects in dose–response curves of hypofractionated radiotherapy of early-stage NSCLC and brain metastases
Creators
- 1. Institute of Physics, Pontificia Universidad Católica de Chile, Santiago de Chile (Chile)
- 2. Department of Medical Physics, Complexo Hospitalario Universitario de Santiago de Compostela (Spain)
- 3. Group of Medical Physics and Biomathematics, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela (Spain)
- 4. Group of Molecular Imaging and Oncology, Instituto de Investigación Sanitaria de Santiago (IDIS), Santiago de Compostela (Spain)
- 5. Department of Radiotherapy, Complexo Hospitalario Universitario de Santiago de Compostela (Spain)
Description
Highlights: • NSCLC dose–response curves show evidence of indirect cell damage at large doses. • Brain metastases dose–response curves show evidence of damage saturation at large doses. • Dose prescription to such tumors might be re-evaluated according to the reported evidence. To investigate the possible contribution of indirect damage and damage saturation to tumour control obtained with SBRT/SRS treatments for early-stage NSCLC and brain metastases.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.radonc.2021.05.012Additional details
Identifiers
- DOI
- 10.1016/j.radonc.2021.05.012;
- PII
- S0167814021062502;
Publishing Information
- Journal Title
- Radiotherapy and Oncology
- Journal Volume
- 161
- Journal Page Range
- p. 1-8
- ISSN
- 0167-8140
- CODEN
- RAONDT
Conference
- Title
- ESTRO 2021
- Dates
- 27-31 Aug 2021
- Place
- Madrid (Spain)
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54014131
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BRAIN; EVALUATION; METASTASES; NEOPLASMS; RADIATION DOSES; RADIOTHERAPY; SIMULATION
- Descriptors DEC
- BODY; CENTRAL NERVOUS SYSTEM; DISEASES; DOSES; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY
Optional Information
- Copyright
- Copyright (c) 2021 The Authors. Published by Elsevier B.V.