Published 2004 | Version v1
Miscellaneous Metadata-only

Study on a combination of sodium peroxodisulphate and irradiation in human ENT tumour and WTS cell lines at different oxygen levels

Creators

  • 1. Martin-Luther Universitaet Halle-Wittenberg, Halle/Saale (Germany). Klinik fuer Strahlentherapie
  • 2. Martin-Luther Universitaet Halle-Wittenberg, Halle/Saale (Germany). Inst. fuer Pathologie

Description

In summary it can be said that sodium peroxodisulphate effectively inhibits tumour cell growth and adds to the effect of single irradiations. On account of its oxidising properties sodium peroxodisulphate appears particularly suitable for use in hypoxic tumours. How sodium peroxodisulphate acts under severely hypoxic conditions remains to be determined by further experimentation

Abstract (German)

Zusammenfassend laesst sich feststellen, dass Natriumperoxodisulfat das Tumorzellwachstum effektiv hemmt bzw. die Effekte einer Einzelbestrahlung additiv verstaerkt. Aufgrund seiner oxidierenden Eigenschaften scheint Natriumperoxodisulfat insbesondere fuer den Einsatz in hypoxischen Tumoren als geeignet. In weiterfuehrenden Experimenten muss jedoch die Wirkung von Natriumperoxodisulfat unter stark hypoxischen Bedingungen getestet werden. (orig.)
Part of:
Experimental radiotherapy and clinical radiobiology. Vol. 13

Additional details

Additional titles

Original title (German)
Untersuchung zur Kombination von Natriumperoxodisulfat und Bestrahlung in humanen HNO-Tumor- und WTS-Zelllinien bei unterschiedlichem Sauerstoffgehalt

Publishing Information

Imprint Title
Experimental radiotherapy and clinical radiobiology. Vol. 13
Imprint Pagination
140 p.
Journal Page Range
p. 23-27
ISSN
1432-864X

Conference

Title
13. symposium on experimental radiotherapy and clinical radiobiology
Original Conference Title
13. Symposium Experimentelle Strahlentherapie und Klinische Strahlenbiologie
Dates
4-6 Mar 2004
Place
Dresden (Germany)

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
36046371
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
ANOXIA; BIOLOGICAL RADIATION EFFECTS; CELL CULTURES; CELL KILLING; CELL PROLIFERATION; EXTERNAL IRRADIATION; IN VITRO; OXYGEN; RADIOSENSITIZERS; RESPONSE MODIFYING FACTORS; TOXICITY; TUMOR CELLS; X RADIATION
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL EFFECTS; DRUGS; ELECTROMAGNETIC RADIATION; ELEMENTS; IONIZING RADIATIONS; IRRADIATION; NONMETALS; RADIATION EFFECTS; RADIATIONS; RESPONSE MODIFYING FACTORS

Optional Information

Notes
Imprint:Experimentelle Strahlentherapie und Klinische Strahlenbiologie. Bd. 13. Proceedings