Telethermographic studies as effect of immunoglobulines (Beriglobin trademark) on thermal radiation caused by high-voltage-irradiation

This study reports on objective thermographic measuring of heat radiation of dermatitides developing in the course of raditherapy in case of female patients receiving postoperative radiotherapy after breast preserving operation on mamma carcinoma. Idea behind this is that immunglobulines affect inflammations of skin induced by irradiation, then also one of theses parameters, in this case heat, would be subject to change. Sixteen patients received 10 ml BeriglobincircledR before first and 5 ml after 5th and 10th radiation (corresponds to 0 Gy, 10 Gy and 20 Gy) as intragluteal injection. Before starting with radiation as well as after 10 Gy respectively applied, upper bodies of patients were examined thermographically until final dose of 50 Gy was reached. Here temperature progress on upper body halves exposed to irradiation was compared with the untreated halves as well as with upper bodies of control group consisting of 20 patients who had received no immunoglobuline injections. Patients who received immunoglobuline injections showed no differences in their skin temperature progress in comparison with the control group. Skin temperature at the beginning as well as temperature progress during treatment and temperature at the end of treatment were identical in both groups. Also the relative temperature increase (temperature of body half subject to irradiation minus temperature of the other body half) was identical in both therapy groups. Immunoglobulines (BeriglobincircledR) do not influence the course of thermal radiation due to dermatitis developing during a series of irradiation treatments. This results in the conclusion, that immunoglobulines do not have any influence in the vasodilatative part of dermatitis and vasodilatative redness respectively. (orig./AJ)