Published March 2001 | Version v1
Journal article Metadata-only

UV-sensitivity of hemoglobin dimers in free state and in valency hybrids modification by serotonin

Creators

  • 1. Voronezhskij Gosudarstvennyj Univ., Voronezh (Russian Federation)

Description

Changes of oxygen-binding activity of hemoglobin dimers modified by the therapeutical doses of UV-light and serotonin in free state and in valency hybrids are analysed. The prior role of photodissociation to dimers at the UV-radiation action on heme-protein molecules has been shown. It has been observed that the complex between hemoglobin serotonin is formed in fields of αβ-dimers contacts

Abstract (Russian)

Проанализированы изменения кислородсвязывающей активности димеров гемоглобина, подвергнутых воздействию серотонина и УФ-света в терапевтических дозах в свободном состоянии и в составе гибридов валентности. Показана преимущественная роль процесса фотодиссоциации гемоглобина на димеры в развитии ответной реакции гембелка на воздействие УФ-радиации. Установлено, что за формирование комплекса гемоглобин-серотонин ответственны области контактов димеров типа αβ

Additional details

Additional titles

Original title (Russian)
UF-чувствительност' димеров гемоглобина в свободном состоянии и в составе гибридов валентности: модификация серотонином

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
41
Journal Issue
2
Journal Page Range
p. 190-194
ISSN
0869-8031
CODEN
RBIREJ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
33020594
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL FUNCTIONS; BIOLOGICAL RADIATION EFFECTS; DIMERS; DISSOCIATION; ERYTHROCYTES; HEMOGLOBIN; MAN; OXYGEN; PHOTOLYSIS; RADIOSENSITIVITY; SEROTONIN; ULTRAVIOLET RADIATION; VALENCE
Descriptors DEC
AMINES; ANIMALS; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENTS; AZAARENES; AZOLES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; DECOMPOSITION; DRUGS; ELECTROMAGNETIC RADIATION; ELEMENTS; GLOBINS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INDOLES; MAMMALS; MATERIALS; NEUROREGULATORS; NONMETALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOTOCHEMICAL REACTIONS; PIGMENTS; PORPHYRINS; PRIMATES; PROTEINS; PYRROLES; RADIATION EFFECTS; RADIATIONS; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; SYMPATHOMIMETICS; TRYPTAMINES; VERTEBRATES

Optional Information

Notes
13 refs.; 5 figs.