Published December 1998 | Version v1
Journal article Metadata-only

Estimate at the nucleotide resolution level of genetic changes in the humans residing in the ecologically unfavourable regions of the Techa river

Creators

  • 1. Inst. Tsitologii i Genetiki SO RAN, Novosibirsk (Russian Federation)
  • 2. Inst. Bioorganicheskoj Khimii SO RAN, Novosibisrk (Russian Federation)
  • 3. Universitet im. Dzh. Mejsona, Fehjrfaks (United States)

Description

To study DNA at the nucleotide level of resolution in residents of settlements located along the Techa river, studies are performed by direct sequencing of gene sequences preliminary amplified and selected by means of analysis of changes of the conformation of DNA unifilament fragments (SSCP-method). Results are presented in details

Abstract (Russian)

С целью изучения ДНК на нуклеотидном уровне разрешения у жителей поселков, расположенных вдоль р. Теча, проведены исследования путем прямого секвенирования генных последовательностей, предварительно ПЦР-амплифированных и отобранных с помощью анализа изменений конформации однонитевых фрагментов ДНК (SSCP-метод). Приводятся подробные результаты исследований

Additional details

Additional titles

Original title (Russian)
Оценка на нуклеотидном уровне генной изменчивости популяции человека в экологически неблагополучных районах реки Теча

Publishing Information

Journal Title
Doklady Akademii Nauk - Rossijskaya Akademiya Nauk
Journal Volume
363
Journal Issue
6
Journal Page Range
p. 831-834
ISSN
0869-5652
CODEN
DAKNEQ

INIS

Country of Publication
Russian Federation
Country of Input or Organization
Russian Federation
INIS RN
32047104
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
CONTAMINATION; CONTROLLED AREAS; DNA; GENETIC RADIATION EFFECTS; ICRP CRITICAL GROUP; RURAL POPULATIONS; TECHA RIVER
Descriptors DEC
BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; GENETIC EFFECTS; HUMAN POPULATIONS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; POPULATIONS; RADIATION EFFECTS; RIVERS; SURFACE WATERS

Optional Information

Notes
14 refs.