Determination of local structures of platinum uridine blues and purples by extended x-ray absorption fine structure spectroscopy

The extended x-ray absorption fine structure analysis of a purple compound derived from the reaction of cis-Pt(cyclopropylamine)2Cl2 with uridine and of a blue compound derived from the reaction of cis-[Pt(NH3)2(H2O2)]2+ with uridine were reported. The local platinum coordination of the two compounds involves Pt-X (where X = N or O) bonds of approximately 2.00 A and a partial but distinct Pt--Pt bond of approximately 2.90 A. The coordination sphere is probably cis-Pt(amine)2XY where X,Y = N3, O2, or O4 of the uridinato ligand