Published 1982 | Version v1
Report Metadata-only

In vitro photoradiation - hematoporphyrin derivative accumulation, sensitization and interaction with ionizing radiation

Creators

Description

Survival after γ-irradiation was measured for CHO cells containing various intracellular hematoporphyrin derivative (Hpd) concentrations with no significant difference in radiosensitivity between control cells and cells containing Hpd. The interaction between ionizing radiation and Hpd photoinactivation was also investigated. Exposure to γ-radiation and Hpd-sensitized photoradiation resulted in survival curves which indicated that damage and/or expression of damage due to each modality interacted in an independent manner at the level (clonogenicity)

Availability note (English)

University Microfilms Order No. 83-03,184.

Additional details

Publishing Information

Imprint Pagination
132 p.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
17022044
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data, Thesis, Non-conventional Literature
Descriptors DEI
CHO CELLS; COMPARATIVE EVALUATIONS; EXPERIMENTAL DATA; GAMMA RADIATION; HEMATOPORPHYRINS; IN VITRO; INJURIES; PHOTOLYSIS; PHOTOSENSITIVITY; RADIOSENSITIVITY; SURVIVAL CURVES
Descriptors DEC
ANIMAL CELLS; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; DATA; DECOMPOSITION; DISEASES; ELECTROMAGNETIC RADIATION; EVALUATION; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; INFORMATION; IONIZING RADIATIONS; NUMERICAL DATA; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PIGMENTS; PORPHYRINS; RADIATIONS; SENSITIVITY; SOMATIC CELLS