Published October 1990 | Version v1
Journal article Metadata-only

Investigation of DNA styrene oxide adducts by 32P-postlabelling in vitro

Creators

  • 1. Research Center for Eco-Environmental Sciences, Academia Sinica (China)

Description

In vitro reaction of DNA with styrene-7,8-oxide (styrene oxide) produced five adducts, as determined by 32P-postlabelling. Chromatographic comarison of the adducts formed in DNA with those formed with the deoxyribonucleotides suggests that deoxyguansoien is the primary site of DNA modification. 32P-postlabelling can be used to investigate DNA adducts formed by styrene oxide

Additional details

Publishing Information

Journal Title
Environmental Chemistry (Beijing)
Journal Volume
9
Journal Issue
5
Series
Environ. Chem. (Beijing).
Journal Page Range
18-26
ISSN
0254-6108
CODEN
HUHUD

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
22083437
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
ADDUCTS; AUTORADIOGRAPHY; CHROMATOGRAPHY; DNA; EPOXIDES; IN VITRO; LABELLED COMPOUNDS; LABELLING; PHOSPHORUS 32; STYRENE
Descriptors DEC
AROMATICS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; HYDROCARBONS; ISOTOPES; LIGHT NUCLEI; NUCLEI; NUCLEIC ACIDS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; PHOSPHORUS ISOTOPES; RADIOISOTOPES; SEPARATION PROCESSES