Modification of macroporous silica gel with polyethylene glycol by exposure to radiation

Samples of KSK-1 macroporous silica gel with a surface modified by different amounts of polyethylene glycol (PEG) have been prepared by exposure to radiation. The influence of the method of coating with 20,000 PEG, the nature of the solvent used, and the radiation dose on its content in the modified samples after prolonged washing with water has been studied. The modified samples have been used to investigate the adsorption of serum albumin from aqueous solutions. The adsorption of albumin on silica gel coated with 1.2-1.5 mg/m2 of polymer is significantly reduced in comparison with the untreated silica gel; no adsorption of protein occurs at PEG contents of > 1.6 mg/m2