Published March 1984 | Version v1
Journal article

A mathematical model of radiation effect on the immunity system

  • 1. Institut Mediko-Biologicheskikh Problem, Moscow (USSR)

Description

A mathematical model, simulating the effect of ionizing radiation on the dynamics of humoral immune reaction is suggested. It represents the system of nonlinear differential equations and is realized in the form of program in Fortran computer language. The model describes the primary immune reaction of nonirradiated organism on T-independent antigen, reflects the postradiation lymphopoiesis dynamics in nonimmunized mammals, simulates the processes of injury and recovery of the humoral immunity system under the combined effect of ionizing radiation and antigenic stimulation. The model can be used for forecasting imminity state in irradiated mammals

Additional details

Additional titles

Original title (Russian)
Математическое моделирование радиационных воздействий на систему иммунитета

Publishing Information

Journal Title
Immunologiya
Journal Issue
no.2
Series
Immunologiya.
ISSN
0300-0567