Published September 30, 1980
| Version v1
Journal article
The procoagulant activity of leukocytes pretreated with radiodetoxified endotoxin
- 1. Debreceni Orvostudomanyi Egyetem (Hungary)
- 2. Orszagos Frederic Joliot-Curie Sugarbiologiai es Sugaregeszseguegyi Kutato Intezet, Budapest (Hungary)
Description
Rabbits were treated with Escherichia coli 089 endotoxin detoxified by ionizing irradiation (60Co-gamma). The leukocytes (PMNs in 90%) obtained from rabbits treated with the mother endotoxin elicited a well defined activity; those obtained from rabbits pretreated with detoxified endotoxin elicited a less pronounced, procoagulant activity. It is suggested that the procoagulant effect may play a part in the mechanism of the local Shwartzman phenomenon. (author)
Additional details
Publishing Information
- Journal Title
- Acta Microbiol. Acad. Sci. Hung.
- Journal Volume
- 27
- Journal Issue
- 3
- Series
- Acta Microbiol. Acad. Sci. Hung.
- Journal Page Range
- 191-194
- ISSN
- 0001-6187
INIS
- Country of Publication
- Hungary
- Country of Input or Organization
- Hungary
- INIS RN
- 12595459
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; COBALT 60; ENDOTOXINS; ESCHERICHIA COLI; GAMMA RADIATION; IN VITRO; LEUKOCYTES; RABBITS; RADIATION DOSES; RADIOIMMUNOLOGY
- Descriptors DEC
- ANIMALS; ANTIGENS; BACTERIA; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; IMMUNOLOGY; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MICROORGANISMS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; TOXINS; VERTEBRATES; YEARS LIVING RADIOISOTOPES
Optional Information
- Notes
- 14 refs.