Published November 1996 | Version v1
Journal article

Problem of pseudomutagenesis. Persistent increased cell change ability induced by radiation and some other agents

  • 1. Inst. Ehksperimental'noj Meitsiny RAMN, Sankt-Peterburg (Russian Federation)

Description

paper presents new data obtained using mammal cells proving the point of view concerning the fact that pseudo mutagenesis is one of private manifestation of more general radiation-induced variation regularities of cells (including phenotypical one) occurring with participation of the directed controlled factors. Endothelium of myocardium capillaries of white mongrel male rates exposed to general or local irradiation (heart or intestines) using RUM-17 X-ray apparatus and using 0.5, 2.25, 4.5 Gy; 9 and 30 Gy; 9 and 18 Gy doses, respectively were studied. Unusual phenomenon of persistent increase of probability of cell damage similar for a number of symptoms to the described earlier for various unicellular specimens was detected. Non-stochastic nature of occurrence, quantity, induction possibility, factors and non radiation nature differ the effect from the traditionally studied ones

Additional details

Additional titles

Original title (Russian)
К проблеме псевдомутагенеза. Персистирующее повышение уровня изменчивости клеток, индуцируемое радиацией и некоторыми другими агентами

Publishing Information

Journal Title
Radiatsionnaya Biologiya, Radioehkologiya
Journal Volume
36
Journal Issue
6
Journal Page Range
p. 926-931
ISSN
0869-8031
CODEN
RBIREJ

Conference

Title
Scientific conference on radiation and chromosomes. Dedicated to the memory of professor N.V.Luchnik
Original Conference Title
Materialy nauchnoj konferentsii Khromosomy i Radiatsiya, posvyashchennoj pamyati professora N.V.Luchnika
Dates
1996
Place
Obninsk (Russian Federation)

Optional Information

Notes
18 refs., 1 tab., 3 figs.