Published November 1977 | Version v1
Journal article Metadata-only

Correlation between diagnostic 59Fe2+-absorption and serum ferritin concentration in man

Creators

  • 1. Hamburg Univ. (Germany, F.R.). Physiologisch-Chemisches Inst.

Description

A high correlation coefficent r = -0.832 (Psub(r not equal to 0) < 0.0001) was estimated in man for the inverse relationship between the diagnostic 59Fe2+-absorption and the serum ferritin concentration which is very close to the correlations r = -0.88 59Fe2+-absorption and the diffuse cytoplasmic storage iron in the bone marrow macrophages. The increase of the diagnostic 59Fe2+-absorption seems to be an earlier and more sensitive indicator of depleted iron stores whereas the serum ferritin decreases somewhat later during the development of iron deficiency. (orig.)

Abstract (German)

Fuer den Menschen wurde ein hoher Korrelationskoeffizient r = -0,832 (Psub(r ungleich 0) < 0,0001) fuer die umgekehrt proportionale Beziehung zwischen der diagnostischen 59Fe2+-Absorption und der Serumferritinkonzentration geschaetzt, die der Korrelation r = -0,88 fuer die Beziehung zwischen der diagnostischen 59Fe2+-Absorption und dem diffusen, cytoplasmatisch gespeicherten Eisen in den Makrophagen des Knochenmarks nahezu entspricht. Die wachsende diagnostische 59Fe2+-Absorption scheint ein frueheres und empfindlicheres Anzeichen fuer erschoepfte Eisenreserven zu sein, waehrend die Ferritinspiegel im Serum erst in einem spaeteren Stadium des Eisenmangels absinkt. (orig.)

Additional details

Identifiers

DOI
10.1515/znc-1977-11-1227;

Publishing Information

Journal Title
Zeitschrift für Naturforschung C
Journal Volume
32
Journal Issue
11-12
Series
Z. Naturforsch., C.
Journal Page Range
1023-1025
ISSN
1865-7125

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
9386161
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S60: APPLIED LIFE SCIENCES;
Descriptors DEI
ABSORPTION; BONE MARROW CELLS; COMPARATIVE EVALUATIONS; CORRELATIONS; CYTOPLASM; DIAGNOSTIC TECHNIQUES; FERRITIN; IRON 59; MAN; NUCLEAR MEDICINE; RADIONUCLIDE KINETICS; UPTAKE
Descriptors DEC
ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CELL CONSTITUENTS; COMPLEXES; CONNECTIVE TISSUE CELLS; DAYS LIVING RADIOISOTOPES; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; IRON COMPLEXES; IRON ISOTOPES; ISOTOPES; KINETICS; MAMMALS; MEDICINE; NUCLEI; ORGANIC COMPOUNDS; PRIMATES; PROTEINS; RADIOISOTOPES; SOMATIC CELLS; TRANSITION ELEMENT COMPLEXES; VERTEBRATES

Optional Information

Notes
1 fig.; 1 tab.; 11 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent