Imprint smear cytology of pelvic lymph nodes after lymphography and x-ray irradiation

The following observations were made by imprint smear cytology of pelvic lymph nodes in patient with cervical cancer after lymphography and irra diation.1. Influences of lymphographya) As regards size distribution of retictlum cells, a bimodial distribution was observed. A tendency to enlargement of reticulum cells was also observed.b) Appearance of multinuclear histiocytes.2. Cytological changes due to Linac X-ray irra diationa) Nuclei of reticulum cells decreased in size after 2, 000 rad of Linac X-ray irradiation.b) Decrease in cell size was seen in multinu clear histiocytes.c) Enlargement and wide variation of the size of cells and nuclei were observed in plasma cells after 2, 000 rad of radiation (in those cases lymphography was performed and positive metastasis revealed).d) Many of metastatic squamous cell carcinoma cells showed the typical radiation changes.