Synthesis and acylation of 2-butylamine-6-p-bromophenyl imidazo-[2,1-b]-1,3,4-thiadiazole

Present article is devoted to synthesis of new derivatives of condensed thiadiazoles - 2-butyl- and (6-p-bromphenyl-[2,1-b]-1,3,4-thiadiazole)-N-butylamide acetic acid by nucleophilic substitution reaction of 2-bromo-6-n-bromphenyl imidazo-[2,1-b] -1,3,4-thiadiazole with butylamine and acylation of 2-butylamino -6-p-bromphenyl imidazo-[2,1-b]-1,3,4-thiadiazole with acetic anhydride. The structure of heterocycles was determined by means of infrared spectroscopy and elemental analysis.