Published April 1986 | Version v1
Journal article

Effect of the antioxidant dibunol on adrenocortical, thyroid, and adenohypopyseal function in adult and old rats

Creators

  • 1. Institute of Gerontology, Acad. of Med. Sci., Kiev

Description

This paper studies the effect of dibunol (4-methyl-2,6-di-tert-butylphenol) (D) on the function of the adrenal cortex, thyroid gland, and adenhypophysis, which produces trophic hormones for the other two glands. Experiments were carried out on adult rats. After injection of D concentrations of corticosterone (CS), triodothyronine (T3), ACTH, and thyrotrophin (TSH) in the blood plasma and the CS concentration in tssue of the adenohypophysis were determined. It is shown that injection of D caused biphasic changes in the CS concentration in both tissues studied in adult and old animals

Additional details

Publishing Information

Journal Title
Bull. Exp. Biol. Med. (Engl. Transl.)
Journal Volume
100
Journal Issue
12
Series
Bull. Exp. Biol. Med. (Engl. Transl.).
Journal Page Range
1609-1611
ISSN
0007-4888
CODEN
BEXBA

Optional Information

Notes
Cover-to-cover translation of Byulleten' Ehksperimental'noj Biologii i Meditsiny (USSR).