Published February 2010 | Version v1
Journal article

Nano-particles for therapeutical purposes: an innovative approach for the radiotherapy of cancer

  • 1. Nanobiotix, 75 - Paris (France)

Description

Nano-technology can be used to manage and assemble substances in unprecedented ways in the history of products for human health. Underlying this revolution are the possibilities for using new therapeutic processes and separating a drug's various functions (distribution, effects, etc.). This is not possible with classical drugs. Nano-medicine has made it possible to develop new approaches to treating cancer, by using nano-particles with physical effects at the scale of the malignant cell. Hard metallic oxide nano-particles have been designed so that they can play a therapeutic role when activated by x-rays. The x-rays irradiation will free electrons from the metallic oxide, these electrons will lose energy through collisions with water molecules and will create free radicals in the cells. These free radicals are very reactive and will damage the covalent bounds of the molecules located around the nano-particles. Clinical tests on man are expected to begin very soon. These 'x-ray-activable' nano-particles might set off a revolution in the practice of radiotherapy for destroying or controlling malignant tumors

Additional details

Additional titles

Original title (French)
Les nanoparticules therapeutiques: une voie novatrice pour la radiotherapie appliquee a la cancerologie

Publishing Information

Journal Title
Realites Industrielles
Journal Issue
no.1
Journal Page Range
p. 39-47
ISSN
1148-7941
CODEN
REAIE7

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
41110029
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
INTERNAL IRRADIATION; NANOSTRUCTURES; NEOPLASMS; RADIOTHERAPY
Descriptors DEC
DISEASES; IRRADIATION; MEDICINE; NUCLEAR MEDICINE; RADIOLOGY; THERAPY