Published 2023 | Version v1
Journal article

EANM enabling guide. How to improve the accessibility of clinical dosimetry

  • 1. Joint Department of Physics, Royal Marsden NHSFT & Institute of Cancer Research, Sutton (United Kingdom)
  • 2. Department of Physics, University of Oslo, Oslo (Norway)
  • 3. Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo (Norway)
  • 4. Department of Nuclear Medicine, Universitair Ziekenhuis Leuven, Louvain (Belgium)
  • 5. Institute of Radiation Physics, Lausanne University Hospital, University of Lausanne, Lausanne (Switzerland)
  • 6. Sweden & Section of Medical Physics, Department of Immunology, Genetics and Pathology, Uppsala University, 751 85, Uppsala (Sweden)
  • 7. Section of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala (Sweden)
  • 8. Department of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Str. 6, 97080, Würzburg (Germany)
  • 9. Radiation Research Unit, Department of Medical Imaging and Radiation Sciences, Istituto Europeo Di Oncologia, IRCCS, Milan (Italy)
  • 10. Nuclear Medicine Unit, University Hospital "Mater Domini, Catanzaro (Italy)
  • 11. Department of Experimental and Clinical Medicine, Neuroscience Research Centre, PET/RM Unit, "Magna Graecia" University of Catanzaro, Catanzaro (Italy)
  • 12. Department of Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam (Netherlands)
  • 13. GIGA-CRC in Vivo Imaging, University of Liège, Liège (Belgium)
  • 14. Division of Nuclear Medicine and Oncological Imaging, University Hospital of Liège, Liège (Belgium)
  • 15. Clinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona (Switzerland)
  • 16. German Cancer Consortium (DKTK)-University Hospital Essen, Essen (Germany)
  • 17. Department of Nuclear Medicine, University of Duisburg-Essen, Duisburg (Germany)
  • 18. Department of Applied Physics, Faculty of Engineering, UPV/EHU, Bilbao (Spain)
  • 19. Department of Medical Physics and Radiation Protection, Gurutzeta-Cruces University Hospital/Biocruces Health Research Institute, Barakaldo (Spain)

Description

Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.

Availability note (English)

Available from: http://dx.doi.org/10.1007/s00259-023-06226-z

Additional details

Identifiers

Publishing Information

Journal Title
European Journal of Nuclear Medicine and Molecular Imaging
Journal Volume
50
Journal Issue
7
Journal Page Range
p. 1861-1868
ISSN
1619-7070
CODEN
EJNMA6

Optional Information

Notes
Oncology #En Dash# Genitourinary