Published 2011
| Version v1
Journal article
The application of amorphous track models to study cell survival in heavy ions beams
- 1. Polish Academy of Science, Inst. of Nuclear Physics, Ul. Radzikowskiego 152, 31-342 Krakow (Poland)
- 2. Div. of Medical Physics in Radiation Oncology, German Cancer Research Center DKFZ, Im Neuenheimer Feld 280, D-69120 Heidelberg (Germany)
- 3. Inst. of Physics, Jagiellonian Univ., Ul. Reymonta 4, 30-059 Krakow (Poland)
- 4. The Maria Sklodowska-Curie Centre of Oncology, Krakow Div., Ul. Garncarska 11, 31-115 Krakow (Poland)
Description
In a study of amorphous track models, in the local effect model (LEM), the Kellerer algorithm was used, which folds radial dose distributions from different ion tracks. In representative set of 10 experimental cell survival curves of normal human skin fibroblast cells irradiated with carbon ions, the method that applies the Kellerer algorithm was found to be more accurate and 104 times faster than the usual Monte Carlo summation method based on a regular grid. (authors)
Availability note (English)
Available from doi: http://dx.doi.org/10.1093/rpd/ncq516Additional details
Identifiers
- DOI
- 10.1093/rpd/ncq516;
Publishing Information
- Journal Title
- Radiation Protection Dosimetry
- Journal Volume
- 143
- Journal Issue
- 2-4
- Journal Page Range
- p. 232-236
- ISSN
- 0144-8420
Conference
- Title
- 15. International Symposium on Microdosimetry - An Interdisciplinary Meeting on Ionising Radiation Quality, Molecular Mechanisms, Cellular Effects, and their Consequences for Low Level Risk Assessment and Radiation Therapy
- Acronym
- MICROS 2009
- Dates
- 25-30 Oct 2009
- Place
- Verona (Italy)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- France
- INIS RN
- 43077666
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S61: RADIATION PROTECTION AND DOSIMETRY; S97: MATHEMATICAL METHODS AND COMPUTING;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ALGORITHMS; BIOLOGICAL MODELS; CARBON IONS; COMPUTERIZED SIMULATION; DOSE-RESPONSE RELATIONSHIPS; FIBROBLASTS; HEAVY IONS; HUMAN POPULATIONS; LET; MONTE CARLO METHOD; PARTICLE TRACKS; RADIATION DOSE DISTRIBUTIONS; SKIN
- Descriptors DEC
- ANIMAL CELLS; BODY; CALCULATION METHODS; CHARGED PARTICLES; CONNECTIVE TISSUE CELLS; ENERGY TRANSFER; IONS; MATHEMATICAL LOGIC; ORGANS; POPULATIONS; SIMULATION; SOMATIC CELLS
Optional Information
- Notes
- 9 refs