Published September 13, 2010 | Version v1
Journal article

Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets

  • 1. Department of Radiotherapy and Radiooncology, Universitätsmedizin Göttingen (Germany)

Description

Stereotactic-Radio-Surgery (SRS) using Conformal-Arc-Therapy (CAT) is a well established irradiation technique for treatment of intracranial targets. Although small safety margins are required because of very high accuracy of patient positioning and exact online localisation, there are still disadvantages like long treatment time, high number of monitor units (MU) and covering of noncircular targets. This planning study analysed whether Rapid Arc (RA) with stereotactic localisation for single-fraction SRS can solve these problems. Ten consecutive patients were treated with Linac-based SRS. Eight patients had one or more brain metastases. The other patients presented a symptomatic vestibularis schwannoma and an atypic meningeoma. For all patients, two plans (CAT/RA) were calculated and analysed. Conformity was higher for RA with additional larger low-dose areas. Furthermore, RA reduced the number of MU and the treatment time for all patients. Dose to organs at risk were equal or slightly higher using RA in comparison to CAT. RA provides a new alternative for single-fraction SRS irradiation combining advantages of short treatment time with lower number of MU and better conformity in addition to accuracy of stereotactic localisation in selected cases with uncomplicated clinical realization

Availability note (English)

Available from http://dx.doi.org/10.1186/1748-717X-5-77; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949676

Additional details

Publishing Information

Journal Title
Radiation Oncology (Online)
Journal Volume
5
Journal Page Range
p. 77
ISSN
1748-717X

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
47061595
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
IRRADIATION; LINEAR ACCELERATORS; PATIENTS; RADIOTHERAPY; SAFETY MARGINS; SURGERY
Descriptors DEC
ACCELERATORS; MEDICINE; NUCLEAR MEDICINE; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c)2010 Wolff et al
Notes
PMCID: PMC2949676; PUBLISHER-ID: 1748-717X-5-77; PMID: 20836871; OAI: oai:pubmedcentral.nih.gov:2949676; licensee BioMed Central Ltd.