Single fraction radiosurgery using Rapid Arc for treatment of intracranial targets
- 1. Department of Radiotherapy and Radiooncology, Universitätsmedizin Göttingen (Germany)
Description
Stereotactic-Radio-Surgery (SRS) using Conformal-Arc-Therapy (CAT) is a well established irradiation technique for treatment of intracranial targets. Although small safety margins are required because of very high accuracy of patient positioning and exact online localisation, there are still disadvantages like long treatment time, high number of monitor units (MU) and covering of noncircular targets. This planning study analysed whether Rapid Arc (RA) with stereotactic localisation for single-fraction SRS can solve these problems. Ten consecutive patients were treated with Linac-based SRS. Eight patients had one or more brain metastases. The other patients presented a symptomatic vestibularis schwannoma and an atypic meningeoma. For all patients, two plans (CAT/RA) were calculated and analysed. Conformity was higher for RA with additional larger low-dose areas. Furthermore, RA reduced the number of MU and the treatment time for all patients. Dose to organs at risk were equal or slightly higher using RA in comparison to CAT. RA provides a new alternative for single-fraction SRS irradiation combining advantages of short treatment time with lower number of MU and better conformity in addition to accuracy of stereotactic localisation in selected cases with uncomplicated clinical realization
Availability note (English)
Available from http://dx.doi.org/10.1186/1748-717X-5-77; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949676Additional details
Identifiers
Publishing Information
- Journal Title
- Radiation Oncology (Online)
- Journal Volume
- 5
- Journal Page Range
- p. 77
- ISSN
- 1748-717X
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 47061595
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- IRRADIATION; LINEAR ACCELERATORS; PATIENTS; RADIOTHERAPY; SAFETY MARGINS; SURGERY
- Descriptors DEC
- ACCELERATORS; MEDICINE; NUCLEAR MEDICINE; RADIOLOGY; THERAPY
Optional Information
- Copyright
- Copyright (c)2010 Wolff et al
- Notes
- PMCID: PMC2949676; PUBLISHER-ID: 1748-717X-5-77; PMID: 20836871; OAI: oai:pubmedcentral.nih.gov:2949676; licensee BioMed Central Ltd.