Preparation of 99mTc-labeled antimony sulfide nanocolloid using tetrahydroborate exchange resin and microwave irradiation

99mTc-Labeled antimony sulfide nanocolloid was prepared by a new labeling method that employed a solid-phase reducing agent or microwave irradiation. Radiolabeling the nanocolloid with 99mTc, the formation of 99mTc-Sb2S3 nanocolloid, was achieved by the solid-phase reducing agent resulting in room temperature reconstitution with Na99mTcO4. Transmission electron microscope showed the mean particle size was estimated to be mostly 7-15 nm. The labeling yield of 99mTc-Sb2S3 was more than 99%. The stability of the labeled product was studied at room temperature and it was found to be excellent