Published October 1986
| Version v1
Journal article
Direct fluorination of melatonin and 5-hydroxy-L-tryptophan with [18F]F2
Creators
- 1. McMaster Univ., Hamilton, Ontario (Canada). Medical Centre
Description
In order that melatonin receptors may be studied in man with positron emission tomography, melatonin labelled with a positron emitting isotope is needed. The preparation of 6-fluoro-melatonin labelled with F-18 is described. Using the same fluorination method, 5-hydroxy-6-(F-18)fluorotryptophan and 4-(F-18)fluoro-5-hydroxy-tryptophan were also prepared. (UK)
Additional details
Publishing Information
- Journal Title
- J. Labelled Compd. Radiopharm.
- Journal Volume
- 23
- Journal Issue
- 10-12
- Series
- J. Labelled Compd. Radiopharm.
- Journal Page Range
- 1101-1102
- ISSN
- 0362-4803
- CODEN
- JLCRD
Conference
- Title
- 6. international symposium on radiopharmaceutical chemistry.
- Dates
- 29 Jun - 3 Jul 1986.
- Place
- Boston, MA (USA).
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 18081954
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- CHEMICAL PREPARATION; FLUORINATION; FLUORINE 18; HYDROXYTRYPTOPHAN; LABELLING; MELATONIN; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS
- Descriptors DEC
- AMINES; AMINO ACIDS; AZOLES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; COMPUTERIZED TOMOGRAPHY; DRUGS; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HALOGENATION; HETEROCYCLIC COMPOUNDS; HOURS LIVING RADIOISOTOPES; HYDROXY ACIDS; INDOLES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NUCLEI; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRROLES; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; SYNTHESIS; TOMOGRAPHY; TRYPTAMINES