Published March 1962 | Version v1
Book Metadata-only

Production of C14-labelled compounds from C14O2 accelerated in an electric field - Physico-chemical analysis of some radioactive compounds obtained

Creators

  • 1. Universite de Liege, Belgique (Belgium)

Description

This paper describes a method of labelling which is based on the acceleration by an electric field of C14O2, which can then react with an organic target in its path. The discharge cell described operates at 500 Y, 150 μA, and the organic products to be labelled are exposed to this field for about three hours with CO2 having a specific activity of 24mc/mmole. The maximum yield remains low (about 6%), and 60% of the C14O2 is destroyed. This maximum activity is obtained only for aliphatic chains (50 μc/g for glutaric acid) or for aromatic substances with an aliphatic chain (acetyl-salicylic acid). (author)

Abstract (French)

Le present memoire expose une methode de marquage basee sur l'acceleration par un champ electrique de 14CO2, qui est alors susceptible d'entrer en reaction avec une cible organique se trouvant dans sa trajectoire. La cellule a decharge decrite fonctionne sous 500 V, 150 μA, et les produits organiques a marquer sont soumis a ce champ pendant environ trois heures, avec du CO2 d'activite specifique 24 mc/mmole. Le rendement maximum obtenu reste faible (6% environ), et 60% du 14CO2 est detruit. Ce rendement maximum n'est obtenu que pour les chaines aliphatiques (50 μc/g pour l'acide glutarique) ou pour des substances aromatiques presentant une chaine aliphatique (acide acetylsalicylique). (author)

Abstract (Spanish)

La memoria describe un metodo de marcacion que consiste en acelerar 14CO2 en un campo electrico para que pueda reaccionar con blancos constituidos por sustancias organicas colocadas en su trayectoria. La celda de descarga que describe la memoria funciona a 500 V y 150 μA, y los productos organicos que se desean marcar se exponen al campo asi creado durante unas tres horas a CO2 de una actividad especifica de 24 mc/mmol. El rendimiento maximo obtenido es bajo (aproximadamente 6%) y el 60% del 14CO2 queda destruido. Este rendimiento maximo solo se alcanza con cadenas alifaticas (50 μc/g para el acido glutarico) o con moleculas ciclicas que presenten una cadena alifatica (acido acetilsalicilico). (author)

Abstract (Russian)

V dannoj rabote izlagaetsya metod mecheniya, osnovannyj na uskorenii ehlektricheskim polem C14O2, kotoryj v ehto vremya poddaetsya vstupleniyu v reaktsiyu s organicheskoj mishen'yu, nakhodyashchejsya na ego traektorii. Opysyvaemaya razryadnaya kamera dejstvuet pod napryazheniem 500 v, 150 mka, a podlezhashchie mecheniyu organicheskie veshchestva vvodyatsya v ehto pole i nakhodyatsya tam okolo 3 chasov vmeste s CO2 udel'noj aktivnosti v 24 mkyuri/mmol'. Maksimal'nyj vykhod poluchennykh produktov ostaetsya slabym (okolo 6%), a 60% C14O2 - razrusheno. EHtot maksimal'nyj vykhod poluchaetsya tol'ko dlya alifaticheskikh tsepej (50 mkkyuri/r dlya glutarovoj kisloty) ili dlya aromaticheskikh veshchestv, predstavlyayushchikh alifaticheskuyu tsep' (atsetilgalitsilovuyu kislotu). (author)
Part of:
Radioisotopes in the Physical Sciences and Industry. Proceedings of the Conference on the Use of Radioisotopes in the Physical Sciences and Industry. V. III

Additional details

Additional titles

Original title (French)
Production de composes marques au

Publishing Information

Publisher
Globus, Druck- und Verlagsanstalt
Imprint Place
Vienna (International Atomic Energy Agency (IAEA))
Imprint Title
Radioisotopes in the Physical Sciences and Industry. Proceedings of the Conference on the Use of Radioisotopes in the Physical Sciences and Industry. V. III
Imprint Pagination
652 p.
Series
Proceedings Series
Journal Page Range
p. 69-72
ISSN
0074-1884

Conference

Title
Conference on the Use of Radioisotopes in the Physical Sciences and Industry
Dates
6-17 Sep 1960
Place
Copenhagen (Denmark)

INIS

Country of Publication
International Atomic Energy Agency (IAEA)
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
43113002
Subject category
S07: ISOTOPES AND RADIATION SOURCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CARBON 14; CARBON DIOXIDE; CHEMICAL ANALYSIS; ELECTRIC FIELDS; GLUTARIC ACID; LABELLED COMPOUNDS; LABELLING; SALICYLIC ACID
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBON COMPOUNDS; CARBON ISOTOPES; CARBON OXIDES; CARBOXYLIC ACIDS; CHALCOGENIDES; DICARBOXYLIC ACIDS; EVEN-EVEN NUCLEI; HYDROXY ACIDS; ISOTOPES; LIGHT NUCLEI; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES

Optional Information

Secondary number(s)
STI/PUB--20(Vol.3)