Published June 1984
| Version v1
Journal article
Lithiated intermediates in the synthesis of 11C labelled compounds: the preparation of D,L-α-[11C]methylornithine and D,L-α-[11C]methylvaline
Creators
- 1. Deutsches Krebsforschungszentrum, Heidelberg (Germany, F.R.). Inst. fuer Nuklearmedizin
Description
A practical method is outlined which permits the effective α-alkylation of amino acids using standard reactive intermediates. Two typical examples of the synthesis are given with the preparation of D,L-α-[11C]methylornithine and D,L-αC]methylvaline. (author)
Additional details
Publishing Information
- Journal Title
- Int. J. Appl. Radiat. Isot.
- Journal Volume
- 35
- Journal Issue
- 6
- Series
- Int. J. Appl. Radiat. Isot.
- Journal Page Range
- 559-561
- ISSN
- 0020-708X
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 15061040
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- ALKYLATION; AMIDES; AMINO ACIDS; CARBON 11; CHEMICAL PREPARATION; ENZYME INHIBITORS; INFRARED SPECTRA; LITHIUM COMPOUNDS; METHYL IODIDE; NMR SPECTRA; ORNITHINE; RADIOPHARMACEUTICALS; SCHIFF BASES; THIN-LAYER CHROMATOGRAPHY; VALINE
- Descriptors DEC
- ALKALI METAL COMPOUNDS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; CHROMATOGRAPHY; DRUGS; EVEN-ODD NUCLEI; IMINES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; SPECTRA; SYNTHESIS