Electromagnetic radiation from memristor applied to basal ganglia helps in controlling absence seizures

We study a model modified from basal ganglia corticothalamic network to explore the occurrence of absence seizures under the effect of electromagnetic radiation from a memristor. Absence seizure activities have been studied by varying the coupling strength of TRN-SRN pathway and the synaptic kinetics of ${\text{GABA}}_B$ receptors on TRN. It has been seen from the numerical simulations that when electromagnetic radiation from a memristor is applied to basal ganglia, spike and wave discharge oscillation region characteristic of absence seizure phenomenon has been reduced considerably. The combined action of electromagnetic radiation and inhibitory SNr-TRN and SNr-SRN pathways has also been investigated. The results show that presence of electromagnetic radiation aids in suppressing the formation of absence seizure activities in corticothalamic system. Our computational results may help to provide an insight in the treatment of real absence epilepsy patients.