Published May 1986 | Version v1
Journal article Metadata-only

Autoradiographic measurement of relative changes in ornithine decarboxylase in axotomized superior cervical ganglion neurons

Creators

  • 1. Veterans Administration Hospital, Washington, DC

Description

An autoradiographic method is described for detecting changes in ornithine decarboxylase in axotomized superior cervical ganglion neurons of rats using [3H]difluoromethylornithine. An increase in binding to neurons was seen at 12 h and 1 day after crushing the postganglionic nerves. Binding returned to control values between 3 and 5 days postoperation. The patterns found using this method were in general agreement with prior reports of enzymatic changes in whole ganglia

Additional details

Publishing Information

Journal Title
Exp. Neurol.
Journal Issue
no.2
Series
Exp. Neurol.
ISSN
0014-4886
CODEN
EXNEA

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
17072582
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
AUTORADIOGRAPHY; CHEMICAL BONDS; DECARBOXYLASES; ENZYME ACTIVITY; GANGLIONS; ORNITHINE; TRITIUM COMPOUNDS
Descriptors DEC
AMINO ACIDS; CARBOXYLIC ACIDS; ENZYMES; HYDROGEN COMPOUNDS; LYASES; NERVOUS SYSTEM; ORGANIC ACIDS; ORGANIC COMPOUNDS