Published August 15, 1978 | Version v1
Patent Open

Radioimmunoassay procedure using a stabilized complex

Description

An improved radioimmunoassay procedure involves the use of a stabilized complex of labelled antigen and antibody which has an extended shelf life as compared to the same complex absent the stabilizers. Since the time needed to incubate the mixture of labelled antigen and antibody is eliminated, the time for completing the assay is considerably shortened and simplified. The components for carrying out the procedure are packaged in a kit basically including standard antigen for generation of a standard curve, a stabilized labelled antigen-antibody complex and reference serum, if used. A plurality of stabilizers are used in the complex to provide a shelf life of six weeks or more. 10 claims

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Additional details

Publishing Information

Imprint Pagination
10 p.
IPC:
Int. Cl.A61K43/00;G01N33/00.
IPC
Int. Cl.A61K43/00;G01N33/00.
Patent number
US patent document 4,107,284/A/

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
11522340
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANTIBODIES; ANTIGENS; LABELLING; MEASURING METHODS; RADIOIMMUNOASSAY; STABILITY; TIMING PROPERTIES
Descriptors DEC
ISOTOPE APPLICATIONS; TRACER TECHNIQUES