Published February 1976 | Version v1
Journal article Metadata-only

Response of HeLa cells to irradiation with π- mesons

Creators

  • 1. Saint Bartholomew's Hospital, London (UK)

Description

Hela cell suspensions were irradiated at various depths of Perspex in a beam of 70 MeV π- mesons. The dose-rate in the Bragg peak varied between 40 rad hour-1 and 150 rad hour -1. The cells were assayed in vitro for loss of reproductive integrity. The results for irradiation in the peak indicated an RBE of about 2.1 when compared to the response obtained using 60Co γ-rays at comparable dose-rates. At dose-rates of 100 to 150 rad hour-1, the RBE peak-to-plateau was about 1.4, whilst at lower dose-rates, the RBE peak-to-plateau was about 1. (author)

Additional details

Identifiers

DOI
10.1259/0007-1285-49-578-166;

Publishing Information

Journal Title
The British Journal of Radiology
Journal Volume
49
Journal Issue
578
Series
Br. J. Radiol.
Journal Page Range
166-171
ISSN
0007-1285

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
7242137
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CELL PROLIFERATION; CLONE CELLS; DEPTH DOSE DISTRIBUTIONS; DOSE RATES; GAMMA RADIATION; HELA CELLS; IN VITRO; MEV RANGE 10-100; PION BEAMS; PIONS MINUS; RADIATION QUALITY; RBE; SURVIVAL CURVES; VIABILITY
Descriptors DEC
ANTIMATTER; ANTIMESONS; ANTIPARTICLES; BEAMS; BIOLOGICAL EFFECTS; BOSONS; CELL CULTURES; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; ENERGY RANGE; HADRONS; IONIZING RADIATIONS; MATTER; MESON BEAMS; MESONS; MEV RANGE; PARTICLE BEAMS; PSEUDOSCALAR ANTIMESONS; PSEUDOSCALAR MESONS; RADIATION DOSE DISTRIBUTIONS; RADIATION EFFECTS; RADIATIONS; SPATIAL DOSE DISTRIBUTIONS

Optional Information

Notes
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