Diabetic dyslipidemia and association of glycemic status with lipid profile, body mass index and abdominal obesity

Objective: To determine the frequency of diabetic dyslipidemia and its association of glycemic status with lipid profile, body mass index and abdominal obesity. Methodology: The study was conducted at District Head Quarter Hospital, Jamshoro @Kotri and included 134 patients with Type 2 Diabetes Mellitus. Blood sample was analyzed for hemoglobin A1C, total cholesterol (TC), high density lipoprotein (HDL), triglycerides (TGs), and low-density lipoprotein (LDL). BMI and waist hip ratio were calculated and analyzed by SPSS version 22.0 Result: Among 134 patients, 92(68.66%) had dyslipidemia. When glycemic status was compared among normal (n=28), overweight (n=66) and obese (n=40), diabetic patients glycemic status was >8.0 among 11(39.3%) normal BMI, 52(78.8%) overweight and 29(72.5%) obese. Anthropometric variations and lipid profile compared between the diabetic people with glycemic control of HbA1c 8.0%(n=92) by independent test. P value was statistically significant for waist hip ratio, waist circumference, BMI and HDL levels while it was insignificant for serum cholesterol, triglycerides, LDL and VLDL levels. Conclusion: There was strong direct association of increased glycemic status among diabetic dyslipidemic patients with abdominal obesity, decreased HDL levels and increase in BMI. (author)