Published 2008 | Version v1
Journal article Metadata-only

Synthesis of 1-indanones through the intramolecular Friedel-Crafts acylation reaction using NbCl5 as Lewis acid

Creators

  • 1. Universidade de Sao Paulo, Ribeirao Preto, SP (Brazil). Faculdade de Filosofia, Ciencias e Letras. Dept. de Quimica

Description

The intramolecular Friedel-Crafts acylation reaction of 3-arylpropanoic acids to give 1-indanones can be effected in good yields under mild conditions (room temperature) by using niobium pentachloride. Our results indicate that NbCl5 acts both as reagent (to transform carboxylic acids into acyl chlorides) and as catalyst in the Friedel-Crafts cyclization. (author)

Availability note (English)

Available from http://www.scielo.br/pdf/qn/v31n4/a10v31n4.pdf

Additional details

Additional titles

Original title (Portuguese)
Sintese de 1-indanones atraves da reacao de acilacao de Friedel-Crafts

Identifiers

URL
http://www.scielo.br/pdf/qn/v31n4/a10v31n4.pdf;

Publishing Information

Journal Title
Quimica Nova
Journal Volume
31
Journal Issue
4
Journal Page Range
p. 763-766
ISSN
0100-4042
CODEN
QUNODK

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
39082678
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S75: CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY;
Descriptors DEI
ACETATES; ACETONITRILE; ACYLATION; ARYL RADICALS; CARBON 13; CATALYSTS; CHEMICAL SHIFT; CYCLIZATION; FORMIC ACID; FRIEDEL-CRAFTS REACTION; HEXANE; HYDROGEN 1; INDAN; INFRARED SPECTRA; LEWIS ACIDS; MASS SPECTRA; NIOBIUM CHLORIDES; NMR SPECTRA; PROPANOLS; SILICA GEL
Descriptors DEC
ADSORBENTS; ALCOHOLS; ALKANES; AROMATICS; CARBON ISOTOPES; CARBOXYLIC ACID SALTS; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; CHLORIDES; CHLORINE COMPOUNDS; EVEN-ODD NUCLEI; HALIDES; HALOGEN COMPOUNDS; HYDROCARBONS; HYDROGEN COMPOUNDS; HYDROGEN ISOTOPES; HYDROXY COMPOUNDS; INORGANIC ACIDS; INORGANIC COMPOUNDS; ISOTOPES; LIGHT NUCLEI; MONOCARBOXYLIC ACIDS; NIOBIUM COMPOUNDS; NITRILES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADICALS; REFRACTORY METAL COMPOUNDS; SPECTRA; STABLE ISOTOPES; TRANSITION ELEMENT COMPOUNDS

Optional Information

Notes
16 refs., 20 figs., 3 tabs.