Granulocyte reserve and the state of blood system granulocytes in patients with uterine cervix carcinoma during radiotherapy

Granulocyte reserve, the state of granulocytes of the blood system in patients with unterine cervix carcinoma in case of combined radiotherapy course have been studied. The insufficiency of granulocyte reserve exhibited itself most vividly in the late reaction of the growth of leukocyte number after injection of nucleic sodium, and in the absence of retrieval to the initial level up to 24h after the injection. A close correlation is noted between the level of granulocytes of peripheral blood and their reserve. The development of leukopenia has been observed up to the end of treatment in persons with an insufficiency of granulocyte reserve at the beginning of the treatment. A low level of granulocytes in peripheral blood is noted to have place also at a sufficient marrow nuclidity and a considerable granulocyte reserve of leukocytes of the blood system. It is stressed that consideration should be given not only to fluctuations of the number of peripheral blood granulocytes, but it is necessary to consider them in a complex with the changes in bone marrow and granulocyte reserve