Published December 1, 2008 | Version v1
Journal article Metadata-only

Effect of porous NiTi alloy on bone formation: A comparative investigation with bulk NiTi alloy for 15 weeks in vivo

Creators

  • 1. School of Materials Science and Engineering, Tianjin University, Tianjin 300072 (China)
  • 2. Department of Materials Science and Engineering, Tianjin University of Technology, Tianjin 300191 (China)
  • 3. School of Dentistry, Tianjin Medical University, Tianjin, 300070 (China)

Description

The purpose of this study is to investigate the effect of porous NiTi alloy on bone formation with a bulk NiTi alloy as a contrast. The porous NiTi alloy prepared by element powder sintering under Ar protection has a porosity of 45% and a mean pore size of 130 μm, and the pores are highly interconnected. The porous and bulk NiTi alloys were bilaterally implanted into the femurs of rabbits for 15 weeks. The bone-implant interface and bone ingrowth were evaluated by undecalcified histological examination under light and fluorescent microscope as well as environmental scanning electron microscope (ESEM). The results show: osteoblasts are very active with fast proliferation and no adverse tissue reaction occurs for the porous NiTi alloy after 15 weeks implantation; porous NiTi alloy has better osteoconductivity and osteointegration than the bulk one; the osteoblasts can ingrow the pores of porous NiTi implant, and direct bone-implant interface can be observed by fluorescent light microscope

Availability note (English)

Available from http://dx.doi.org/10.1016/j.msec.2007.11.010

Additional details

Identifiers

DOI
10.1016/j.msec.2007.11.010;
PII
S0928-4931(07)00250-0;

Publishing Information

Journal Title
Materials Science and Engineering. C, Biomimetic Materials, Sensors and Systems
Journal Volume
28
Journal Issue
8
Journal Page Range
p. 1271-1275
ISSN
0928-4931

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
40075266
Subject category
S36: MATERIALS SCIENCE;
Descriptors DEI
CONNECTIVE TISSUE CELLS; FEMUR; FLUORESCENCE; INTERFACES; NICKEL ALLOYS; POROSITY; POROUS MATERIALS; POWDERS; SCANNING ELECTRON MICROSCOPY; SINTERING; TITANIUM ALLOYS
Descriptors DEC
ALLOYS; ANIMAL CELLS; BODY; ELECTRON MICROSCOPY; EMISSION; FABRICATION; LUMINESCENCE; MATERIALS; MICROSCOPY; ORGANS; PHOTON EMISSION; SKELETON; SOMATIC CELLS; TRANSITION ELEMENT ALLOYS

Optional Information

Copyright
Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.