Published January 26, 1978 | Version v1
Journal article Metadata-only

Differential inhibitory effect of 5-fluorouridine on RNA labelling in dipteran salivary gland cells

Creators

  • 1. Karolinska Institutet, Stockholm (Sweden). Dept. of Histology

Description

In Chironomus salivary glands, 5-fluouridine inhibits 3H-labelling of ribosomal RNA. The drug does not prevent 3H-labelling of other types of RNA-like heterodisperse messenger-like RNA, 75-S RNA of Balbiani ring origin and 4-S RNA which furthermore are exported to cytoplasm. 3H-adenosine was used as RNA precursor and injected into the animals. The labelled salivary gland RNA was analysed by gel electrophoresis

Additional details

Identifiers

DOI
10.1016/0005-2787(78)90054-0;

Publishing Information

Journal Title
Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
Journal Volume
517
Journal Issue
1
Series
Biochim. Biophys. Acta - Nucl. Acids Protein Synth.
Journal Page Range
265-268
ISSN
0006-3002; 0007-2787

INIS

Country of Publication
Netherlands
Country of Input or Organization
Netherlands
INIS RN
9373769
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
FLIES; IN VIVO; INHIBITION; INJECTION; LABELLING; METABOLISM; ORGANIC FLUORINE COMPOUNDS; RNA; SALIVARY GLANDS; TRITIUM COMPOUNDS; URIDINE
Descriptors DEC
ANIMALS; ARTHROPODS; AZINES; BODY; GLANDS; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; INSECTS; INTAKE; INVERTEBRATES; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PYRIMIDINES; RIBOSIDES; URACILS

Optional Information

Notes
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