Published April 2018 | Version v1
Journal article

Regioselective synthesis of pyridines by redox alkylation of pyridine N-oxides with malonates

  • 1. University of Vienna, Institute of Organic Chemistry (Austria)

Description

A regioselective synthesis of pyridines by the addition of malonate anions to pyridine N-oxide derivatives, which have been activated by trifluoromethanesulfonic anhydride, is reported. The reaction selectively affords either 2- or 4-substituted pyridines in good yields. Graphical abstract: .

Additional details

Identifiers

Publishing Information

Journal Title
Monatshefte fuer Chemie
Journal Volume
149
Journal Issue
4
Journal Page Range
p. 715-719
ISSN
0026-9247
CODEN
MOCHAP

Conference

Title
17. blue Danube symposium on heterocyclic chemistry
Dates
30 Aug - 2 Sep 2017
Place
Linz (Austria)

INIS

Country of Publication
Austria
Country of Input or Organization
Austria
INIS RN
50003509
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; S77: NANOSCIENCE AND NANOTECHNOLOGY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ALKYLATION; ANHYDRIDES; ANIONS; OXIDES; PYRIDINE; SYNTHESIS
Descriptors DEC
AZINES; CHALCOGENIDES; CHARGED PARTICLES; CHEMICAL REACTIONS; HETEROCYCLIC COMPOUNDS; IONS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; OXYGEN COMPOUNDS; PYRIDINES

Optional Information

Copyright
Copyright (c) 2018 The Author(s)