Published July 11, 1975
| Version v1
Patent
Drugs composed of polysaccharides obtained from lipopolysaccharides extracted from bacteria
Description
This invention concerns a protection and control agent against irradiation in living beings, composed of polysaccharides, called PS, obtained from lipopolysaccharides (LPS), which in turn are extracted from Gram-negative bacteria after separation of the major part and preferably all the initial lipid content of these LPS's. The molecular weight of the PS ingredients, once purified, is between 8,000 and 35,000 and mainly around 10,000. They contain: around 50 to 70% carbon hydrates by weight; around 1 to 8% hexoamines by weight; around 1 to 5% amino-compounds, among which 1 to 2% amino-acids by weight less than 1% and preferably no fatty acids or lipids and their phosphorus content is around 0.2 to 0.5% by weight
Availability note (English)
Available from Institut National de la Propriete Industrielle, Paris (France).Abstract (French)
L'invention concerne un agent de protection et de lutte contre les irradiations chez les etres vivants, constitue de polysaccharides, denomme PS, obtenu a partir de lipopolysaccharides (LPS), eux-memes extraits de bacteries gram negatif apres separation de la majeure partie et, de preference, de la quasi-totalite, de la teneur initiale en lipides des LPS. Le poids moleculaire des constituants du PS, une fois purifie, est compris entre environ 8000 et 35000, et principalement de l'ordre de 10000. Ils contiennent: environ 50 a 70% en poids d'hydrates de carbone; d'environ 1 a 8% en poids d'hexosamines; d'environ 1 a 5% en poids de composes amines parmi lesquels 1 a 2% d'acides amines; moins de 1% et de preference pas d'acides gras ou lipides, et leur teneur en phosphore est d'environ 0,2 a 0,5% en poidsAdditional details
Additional titles
- Original title (French)
- Medicament contenant, a titre de principe actif, un produit a base de polysaccharides, notamment obtenu a partir de lipopolysaccharides bacteriens
Publishing Information
- Imprint Pagination
- 12 p.
- IPC:
- Int. Cl. A61k31/715; A61k35/74; C12d13/04.
- IPC
- Int. Cl. A61k31/715; A61k35/74; C12d13/04.
- Patent number
- FR patent document 2316964/A/
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 10433017
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Non-conventional Literature
- Descriptors DEI
- BACTERIA; CHEMICAL COMPOSITION; POLYSACCHARIDES; RADIOPROTECTIVE SUBSTANCES
- Descriptors DEC
- CARBOHYDRATES; DRUGS; MICROORGANISMS; ORGANIC COMPOUNDS; RESPONSE MODIFYING FACTORS; SACCHARIDES