Published September 1988 | Version v1
Journal article Metadata-only

Radioprotective efficacy of complexes containing copper, cobalt and zinc with substituted acylhydrazones

Creators

  • 1. Voenno-Meditsinskaya Akademiya, Leningrad (USSR)

Description

Acylhydrazone metal complexes belong to a new class of radioprotective agents that have a cytostatic effect increasing, in some cases, the survival rate of irradiated animals by 40-60 per cent compared to irradiated controls. The most active drugs are hypotoxic and applied in much lower doses than ordinary S-containing radioprotective agents to achieve the same protective effect

Additional details

Additional titles

Original title (Russian)
Радиозащитная активност' комплексов меди, кобальта и цинка с замещенными ацилгидразонами

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
28
Journal Issue
5
Series
Radiobiologiya.
Journal Page Range
691-694
ISSN
0033-8192
CODEN
RADOA

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
20029362
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL EFFECTS; COBALT COMPLEXES; COPPER COMPLEXES; GAMMA RADIATION; HYDRAZONES; MICE; RADIATION PROTECTION; TIME DEPENDENCE; TOXICITY; WHOLE-BODY IRRADIATION; ZINC COMPLEXES
Descriptors DEC
ANIMALS; COMPLEXES; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIATIONS; RODENTS; TRANSITION ELEMENT COMPLEXES; VERTEBRATES