Published June 1989
| Version v1
Journal article
Comparison of detectable bleeding rates of radiopharmaceuticals for localization of gastrointestinal bleeding in sheep using a closed system
Creators
- 1. Kuwait Univ. (Kuwait). Dept. of Nuclear Medicine
- 2. Kuwait Univ. (Kuwait). Dept. of Surgery
Description
The closed experimental animal model system was used to compare the detectable gastrointestinal (GI) bleeding rates of 99mTc-DTPA, 99mTc-RBCs and 99mTc tin colloid in sheep. The three radiopharmaceuticals were used to detect the upper GI bleeding sites at rates of 0.57 and 0.25 ml/min. At the lower bleeding rate of 0.1 ml/min, both 99mTc-DTPA and 99mTc-RBCs were successful in detecting the bleeding site. At the lowest rate of 0.07 ml/min only 99mTc-DTPA was successful in detecting the bleeding site. The results indicate that 99mTc-DTPA is the most useful 99mTc radiopharmaceutical for detecting the upper GI bleeding site at the slowest bleeding rate studied. (orig.)
Abstract (German)
Es wurde ein geschlossenes Tiermodell (Schaf) verwendet, um die nachweisbaren Blutungsraten von 99mTc-DTPA, 99mTc-RBCs und 99mTc-Zinn-Kolloid zu vergleichen. Die 3 Radiopharmaka wurden benutzt, um obere gastrointestinale Blutungsquellen bei Flussraten von 0,57 und 0,25 ml/min nachzuweisen. Bei der geringen Blutungsrate von 0,1 ml/min konnte die Blutungsstelle sowohl mit 99mTc-DTPA als auch mit 99mTc-RBCs nachgewiesen werden. Die geringste Blutungsrate von 0,07 ml/min konnte nur mit 99mTc-DTPA nachgewiesen werden. Die Ergebnisse zeigen, dass 99mTc-DTPA das am besten geeignete Radiopharmakon zum Nachweis oberer gastrointestinaler Blutungen bei der geringsten verwendeten Blutungsrate ist. (orig.)Additional details
Publishing Information
- Journal Title
- Nuc Compact
- Journal Volume
- 20
- Journal Issue
- 3
- Series
- Nuc Compact.
- Journal Page Range
- 92-95
- ISSN
- 0344-3752
- CODEN
- CNNMA
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 20084470
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ACCURACY; COMPARATIVE EVALUATIONS; DIAGNOSIS; DTPA; ERYTHROCYTES; GASTROINTESTINAL TRACT; HEMORRHAGE; ISOMERIC NUCLEI; LABELLED POOL TECHNIQUES; LABELLING; RADIOCOLLOIDS; RADIOPHARMACEUTICALS; SHEEP; TECHNETIUM COMPLEXES; TECHNETIUM 99
- Descriptors DEC
- AMINO ACIDS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOXYLIC ACIDS; CHELATING AGENTS; COLLOIDS; COMPLEXES; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; DOMESTIC ANIMALS; DRUGS; EVALUATION; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; PATHOLOGICAL CHANGES; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; RUMINANTS; SYMPTOMS; TECHNETIUM ISOTOPES; TRACER TECHNIQUES; TRANSITION ELEMENT COMPLEXES; VERTEBRATES; YEARS LIVING RADIOISOTOPES
Optional Information
- Contract/Grant/Project number
- Grant MN 014