Phytochemical analysis, multi-element composition and biological activities of extracts and lupenone from Albizia inundata (Mart.) Barneby and J.W.Grimes
Creators
- 1. Universidade do Estado da Bahia (UEBA), Salvador, BA (Brazil)
- 2. Fundação Oswaldo Cruz (FIOCRUZ), Salvador, BA (Brazil)
- 3. Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil)
- 4. Universidade Estadual de Feira de Santana (UEFS), BA (Brazil)
- 5. Universidade Federal do Recôncavo da Bahia (UFRB), Cruz das Almas, BA (Brazil)
Description
In this study, antimicrobial activity of extracts and lupenone from A. inundata (Fabaceae, Mimosoideae), were tested. In addition, the multi-element composition of the leaves, bark and stems (heartwood) of A. inundata was evaluated using inductively coupled plasma optical emission spectrometry (ICP OES). Lupenone was isolated in the petroleum ether extract of leaves, for the first time. Biological assays were conducted to evaluate the antimicrobial (antibacterial, antifungal and antiparasitic) of extracts, their fractions and lupenone. The results showed antimicrobial and antileishmanial activity of these compounds, which may be useful for obtaining a chemical composition and biological activity database on Albizia species. For multi-element composition, we found the mean concentrations (minimum-maximum) of Al, Ca, Cr, Cu, Fe, K, Mg, Mn, Ni, P, V and Zn in the samples ranged between 0.06 and 265.41 μg g-1. Concentration ranges of Cu, Fe, Mn and Zn are large, which makes these samples as additional sources of these macronutrients. (author)
Additional details
Identifiers
Publishing Information
- Journal Title
- Journal of the Brazilian Chemical Society
- Journal Volume
- 31
- Journal Issue
- 9
- Journal Page Range
- p. 1825-1837
- ISSN
- 0103-5053
INIS
- Country of Publication
- Brazil
- Country of Input or Organization
- Brazil
- INIS RN
- 52022329
- Subject category
- S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- ANTIMICROBIAL AGENTS; CARBON 13; CHEMICAL COMPOSITION; ELEMENTS; HYDROGEN 1; LEAVES; MEDICINAL PLANTS; MULTI-ELEMENT ANALYSIS; NUCLEAR MAGNETIC RESONANCE; TERPENES; THIN-LAYER CHROMATOGRAPHY; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY
- Descriptors DEC
- ANTI-INFECTIVE AGENTS; CARBON ISOTOPES; CHEMICAL ANALYSIS; CHROMATOGRAPHY; DRUGS; ELECTRON MICROSCOPY; EVEN-ODD NUCLEI; HYDROGEN ISOTOPES; ISOTOPES; LIGHT NUCLEI; MAGNETIC RESONANCE; MICROSCOPY; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PLANTS; RESONANCE; SEPARATION PROCESSES; STABLE ISOTOPES