Published 1976 | Version v1
Report Restricted

Comparison of the action of radium 224 and other radioactive elements in the treatment of rheumatoid arthritis

Creators

  • 1. Centre Hospitalier Universitaire, 54 - Nancy (France). Service de Medecine Nucleaire et d'Informatique Medicale

Description

The authors compared 5 radionuclides used in radiosynoviorthesis for the treatment of rheumatic polyarthritis. The excretion after injection into the knee-joints of a number of patient was studied. It was found that only colloidal solutions should be used, and that α and β sources are not effective enough. The chloride of the isotope 224Ra was less effective than the corresponding 198Au, 169Er, 90Y, and 186Re compounds. The clinical findings in more than 450 cases confirm these assumptions. (MG)

Availability note (English)

MF available from INIS under the Report Number.

Abstract (German)

Die Autoren stellten einen Vergleich zwischen 5 Radionukliden an, die in der Radiosynoviorthese zur Behandlung der rheumatischen Polyarthritis angewendet werden. Es wurde die Ausscheidung nach Injektion in das Kniegelenk von mehreren Patienten untersucht. Es stellte sich heraus, dass nur kolloidale Loesungen Verwendung finden sollten und dass die Alpha- und Gammastrahler nich vorteilhaft sind. Das Chlorid des Isotops 224Ra erwies sich als weniger geeignet als die entsprechende 198Au-, 169Er-,90Y- und 189 Re-Verbindung. Die klinischen Resultate von mehr als 450 Faellen bestaetigten diese Annahme. (MG)

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Additional details

Publishing Information

Imprint Pagination
5 p.
Report number
AED-Conf--76-430-002

Conference

Title
2. international symposium on biological effects of Ra-224.
Dates
20 Sep 1976.
Place
Neuherberg/Muenchen, Germany, F.R.

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
8296232
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S60: APPLIED LIFE SCIENCES; S61: RADIATION PROTECTION AND DOSIMETRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL HALF-LIFE; COLLOIDS; ERBIUM CHLORIDES; ERBIUM 169; EXCRETION; GOLD CHLORIDES; GOLD 198; PARTICLE SIZE; PATIENTS; RADIATION DOSES; RADIONUCLIDE KINETICS; RADIOTHERAPY; RADIUM CHLORIDES; RADIUM 224; RETENTION; RHENIUM CHLORIDES; RHENIUM 186; RHEUMATIC DISEASES; SKELETON; YTTRIUM CHLORIDES; YTTRIUM 90
Descriptors DEC
ALKALINE EARTH METAL COMPOUNDS; ALPHA DECAY RADIOISOTOPES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CHLORIDES; CHLORINE COMPOUNDS; CLEARANCE; DAYS LIVING RADIOISOTOPES; DISEASES; DISPERSIONS; ELECTRON CAPTURE RADIOISOTOPES; ERBIUM COMPOUNDS; ERBIUM ISOTOPES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; GOLD COMPOUNDS; GOLD ISOTOPES; HALIDES; HALOGEN COMPOUNDS; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KINETICS; MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPES; RADIUM COMPOUNDS; RADIUM ISOTOPES; RARE EARTH COMPOUNDS; RARE EARTH NUCLEI; RHENIUM COMPOUNDS; RHENIUM ISOTOPES; SIZE; SKELETAL DISEASES; THERAPY; TRANSITION ELEMENT COMPOUNDS; YTTRIUM COMPOUNDS; YTTRIUM ISOTOPES