Published 2008
| Version v1
Journal article
Radiochemical studies relevant to the no-carrier-added production of 61,64Cu at a cyclotron
- 1. Faculty of Engineering, Research and Science Campus, Islamic Azad Univ., Tehran (Iran, Islamic Republic of)
- 2. Cyclotron Dept., Nuclear Research Center for Agriculture and Medicine (NRCAM), Karaj (Iran, Islamic Republic of)
- 3. Cyclotron Dept., Chilean Nuclear Energy Commission, Santiago (Chile)
- 4. Faculty of Engineering, Univ. of Talca (Chile)
Description
Copper-64 (t1/2 = 12.7 h) is a promising cancer treatment radiotherapy agent and combines positron emission tomography (PET). It was produced utilizing the 64Ni(p,n)64Cu nuclear reaction channel. Natural nickel was electroplated successfully, 48 μm thick, onto a gold-coated copper backing slab. Bombardment of nickel plated target was performed with 16 MeV protons at a current of 200 μA. Copper-64 together with copper-61 was separated from Ni and other non-isotopic impurities by ion exchange chromatography. The method of separation of radiocopper has been improved. (orig.)
Additional details
Publishing Information
- Journal Title
- Radiochimica Acta
- Journal Volume
- 96
- Journal Issue
- 7
- Journal Page Range
- p. 399-402
- ISSN
- 0033-8230
- CODEN
- RAACAP
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 39091547
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CARCINOMAS; COPPER 61; COPPER 64; CYCLOTRONS; HALF-LIFE; ION EXCHANGE CHROMATOGRAPHY; ISOTOPE SEPARATION; MEV RANGE 10-100; NICKEL 64 TARGET; POSITRON COMPUTED TOMOGRAPHY; PROTON BEAMS; PROTON REACTIONS; RADIOPHARMACEUTICALS; RADIOTHERAPY
- Descriptors DEC
- ACCELERATORS; BARYON REACTIONS; BEAMS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CHARGED-PARTICLE REACTIONS; CHROMATOGRAPHY; COMPUTERIZED TOMOGRAPHY; COPPER ISOTOPES; CYCLIC ACCELERATORS; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; ENERGY RANGE; HADRON REACTIONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; MEDICINE; MEV RANGE; NEOPLASMS; NUCLEAR MEDICINE; NUCLEAR REACTIONS; NUCLEI; NUCLEON BEAMS; NUCLEON REACTIONS; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; PARTICLE BEAMS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RADIOLOGY; SEPARATION PROCESSES; TARGETS; THERAPY; TOMOGRAPHY