Published 1994 | Version v1
Journal article Metadata-only

Comparative investigations of biodistribution of HPD in mice - in normal tissues and mammary carcinoma

Creators

  • 1. Wojskowa Akademia Techniczna, Warsaw (Poland)
  • 2. Wojskowy Inst. Higieny i Epidemiologii, Warsaw (Poland)
  • 3. Wojskowa Akademia Medyczna, Warsaw (Poland)

Description

The paper presents comparative data on biodistribution of HPD in normal tissues of mice and in transplanted spontaneous mammary tumor. We applied radiometric method for studying this problem. HPD was labelled with 65Zn and then was intravenously injected into mouse. Then, the radioactivity of different tissues was measured. Our results indicate that HPD reaches greater concentration in tumor than in other tissues. The highest HPD concentration in tumor develops within the first few hours after its administration. This is the best time for phototherapy in the application in the treatment of mammary tumor. (author). 10 refs, 1 fig., 1 tab

Additional details

Additional titles

Original title (Polish)
Porownawcze badania nad rozmieszczeniem HPD u myszy w tkankach prawidlowych i w raku sutka
Augmented title (English)
using labelled compounds

Publishing Information

Journal Title
Problemy Medycyny Nuklearnej
Journal Volume
8
Journal Issue
16
Journal Page Range
p. 209-213.
ISSN
0860-3405
CODEN
PMNUE6

INIS

Country of Publication
Poland
Country of Input or Organization
Poland
INIS RN
28047013
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
DIAGNOSIS; LABELLED COMPOUNDS; MICE; NEOPLASMS; ZINC 65
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; ISOTOPES; MAMMALS; NUCLEI; RADIOISOTOPES; RODENTS; VERTEBRATES; ZINC ISOTOPES