Fast magnetic resonance imaging for diagnosing pulmonary tuberculosis in children. The sub-10-min unenhanced scan
Creators
- 1. Department of Radiology, Nelson Mandela Children's Hospital, University of the Witwatersrand, Johannesburg (South Africa)
- 2. Red Cross Children's Hospital, Department of Paediatrics & Child Health, Klipfontein Road, Rondebosch, 7700, Cape Town (South Africa)
- 3. Department of Radiology, The Children's Hospital of Philadelphia, Philadelphia, PA (United States)
- 4. The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (United States)
Description
In this study, we aimed to report the feasibility and quality of fast (unenhanced < 10-min duration) magnetic resonance imaging (MRI) for the detection of lymphadenopathy in non-sedated children with suspected tuberculosis (TB). This was a prospective study that involved children (< 13 years of age) hospitalised at Red Cross Children's Hospital with suspected pulmonary TB who were referred for a fast MRI of the chest. The limited short-duration MRI protocol included coronal short tau inversion recovery (STIR) and axial diffusion-weighted imaging (DWI) sequences with additional axial STIR and axial and coronal T2 sequences if the patient was compliant. The scan time was capped at 10 min and a study was considered successfully completed when DWI and STIR images were obtained in axial planes. MRI quality was recorded as 'acceptable quality'; 'poor quality, but readable'; and 'non-diagnostic'. Of the 192 fast MRI protocol scans, 166 (86%) were successfully completed within the 10-min allotted scan period. There was no age or sex difference between successful and unsuccessful studies. The mean duration of successful scans was 6.5 min (standard deviation = 1.5 min, range = 4-10 min). Fast (sub-10-min scan) MRI is feasible for diagnosis of lymphadenopathy in non-sedated children in the setting of suspected TB, including those below 6 years of age.
Additional details
Identifiers
Publishing Information
- Journal Title
- Pediatric Radiology
- Journal Volume
- 54
- Journal Issue
- 3
- Journal Page Range
- p. 425-429
- ISSN
- 0301-0449
- CODEN
- PDRYA5
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 55039973
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CHEST; CHILDREN; DATA COMPILATION; DIAGNOSIS; DIFFUSION; IMAGE PROCESSING; LUNGS; NMR IMAGING; RELAXATION TIME; TUBERCULOSIS; WEIGHTING FUNCTIONS
- Descriptors DEC
- AGE GROUPS; ANIMALS; BACTERIAL DISEASES; BODY; DATA; DATA PROCESSING; DIAGNOSTIC TECHNIQUES; DISEASES; FUNCTIONS; HUMANS; INFECTIOUS DISEASES; INFORMATION; MAMMALS; ORGANS; PRIMATES; PROCESSING; RESPIRATORY SYSTEM; VERTEBRATES; ZOONOTIC DISEASES
Optional Information
- Notes
- Special Issue: Global Pediatric Radiology