Published 1976 | Version v1
Book Metadata-only

Pathology of tumors induced in Harwell mice by 239Pu and 226Ra

Creators

  • 1. Medical Research Council, Harwell, Eng.

Description

Single intraperitoneal doses of 226Ra and 239Pu solutions given to Harwell-strain mice, produced mainly osteosarcoma. C3H mice were sensitive and CBA mice more resistant to 226Ra. Plutonium-239 caused additionally lymphoma in CBA and possibly an increase in miscellaneous malignancies. The histology suggests that Ra and Pu produce osteosarcoma in areas of accentuated bone turnover in cortical bone

Additional details

Additional titles

Augmented title (English)
Comparison with C_3H and CBA mice

Publishing Information

Publisher
Univ. of Utah.
Imprint Place
Salt Lake City
Imprint Title
Health effects of plutonium and radium
Imprint Pagination
p. 505-521.

Conference

Title
Workshop on the biological effects and toxicity of Pu 239 and Ra 226.
Dates
6 Oct 1975.
Place
Sun Valley, Idaho, USA.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
7265545
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; DISTRIBUTION; GENETIC VARIABILITY; INTERNAL IRRADIATION; INTRAPERITONEAL INJECTION; LYMPHOMAS; MICE; NEOPLASMS; OSTEOSARCOMAS; PLUTONIUM 239; RADIATION EFFECTS; RADIONUCLIDE ADMINISTRATION; RADIOSENSITIVITY; RADIUM 226; TISSUES
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL VARIABILITY; BODY; DISEASES; EVEN-EVEN NUCLEI; EVEN-ODD NUCLEI; HEAVY NUCLEI; INJECTION; INTAKE; IRRADIATION; ISOTOPES; MAMMALS; NUCLEI; PLUTONIUM ISOTOPES; RADIOISOTOPES; RADIUM ISOTOPES; RODENTS; SARCOMAS; SKELETAL DISEASES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
Imprint:See CONF-751043--.