Published 2008 | Version v1
Journal article Metadata-only

Determination of kryptofix 2.2.2 concentration in [18F] FDG radiopharmaceutical

Creators

  • 1. Atomic Energy Organization of Iran, Nuclear Science and Technology Research Institute, Agricultural, Medical and Industrial Research School, Cyclotron and Nuclear Medicine Department, Karaj (Iran, Islamic Republic of)

Description

Concentration of kryptofix 2.2.2 in [18F]FDG solutions and standard solutions of kryptofix 2.2.2 was determined by two methods: Visualization of combination of K2.2.2 with iodine vapor and iodo platinate reagent. In both methods, concentration difference of K2.2.2 solutions was appeared as difference in color intensity of revealed spots on TLC. The detection limit of K2.2.2 by iodine vapor and iodo platinate reagent is 25 and 2 ppm, respectively. Both methods can be used to release or reject the quality of [18F]FDG radiopharmaceutical for intravenous injection, but the second method is more suitable because of taking shorter time

Availability note (English)

Available from Atomic Energy Organization of Iran

Additional details

Additional titles

Original title (Persian)
Tain-e ghelzat-e kryptofix dar radiodaru-ye [1

Publishing Information

Journal Title
Journal of Nuclear Science and Technology
Journal Issue
no.45
Journal Page Range
p. 39-43
ISSN
1735-1871

INIS

Country of Publication
Iran, Islamic Republic of
Country of Input or Organization
Iran, Islamic Republic of
INIS RN
40011428
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CHEMICAL ANALYSIS; CONCENTRATION RATIO; FLUORINE 18; FLUORODEOXYGLUCOSE; IODINE COMPOUNDS; QUALITY CONTROL; RADIOPHARMACEUTICALS; THIN-LAYER CHROMATOGRAPHY
Descriptors DEC
ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CHROMATOGRAPHY; CONTROL; DIMENSIONLESS NUMBERS; DRUGS; FLUORINE ISOTOPES; HALOGEN COMPOUNDS; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NANOSECONDS LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES