Published March 12, 1980
| Version v1
Journal article
A microcytotoxicity assay using 111indium oxine release from platelets
Description
A simple, rapid method is described for the labelling of platelets with 111indium oxine for use in a microcytotoxicity assay. The assay described gives low levels of spontaneous lysis, good reproducibility and an end point may be determined by autoradiography as well as by direct measurement of release of 111indium. The labelled platelets, stored at 40C without further washing, may be used in the assay system for up to 4 days after preparation without loss of reproducibility. (Auth.)
Additional details
Publishing Information
- Journal Title
- J. Immunol. Methods
- Journal Volume
- 33
- Journal Issue
- 1
- Series
- J. Immunol. Methods.
- Journal Page Range
- 45-53
- ISSN
- 0022-1759
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 11530701
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- ACCURACY; BLOOD PLATELETS; EXPERIMENTAL DATA; GRAPHS; INDIUM 111; LABELLED COMPOUNDS; LABELLING; OPTIMIZATION; PERFORMANCE; RADIOASSAY; TOXICITY
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; DATA; DATA FORMS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; INDIUM ISOTOPES; INFORMATION; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUMERICAL DATA; ODD-EVEN NUCLEI; RADIOISOTOPES