Published February 1981 | Version v1
Journal article Metadata-only

DNA-denaturing effect of irradiated hydrogen peroxide

Creators

  • 1. Goodwin Inst. for Cancer Research, Plantation, FL (USA)

Description

By an acridine dye method for analyzing DNA conformation, it was shown that hydrogen peroxide, in conjunction with irradiation at wave lengths longer than 290 nm, exerted a denaturing effect on linear duplex DNA. The effect was dose-related to a disappearing limit of 10 μM hydrogen peroxide. (author)

Additional details

Publishing Information

Journal Title
Photochem. Photobiol.
Journal Volume
33
Journal Issue
2
Series
Photochem. Photobiol.
Journal Page Range
251-252
ISSN
0031-8655

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
13707796
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ACRIFLAVINE; DILUTION; DNA; DOSE-RESPONSE RELATIONSHIPS; HYDROGEN PEROXIDE; NUCLEIC ACID DENATURATION; RESPONSE MODIFYING FACTORS; ULTRAVIOLET RADIATION
Descriptors DEC
ACRIDINES; AMINES; AZINES; ELECTROMAGNETIC RADIATION; FLAVINES; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; OXYGEN COMPOUNDS; PEROXIDES; PYRIDINES; RADIATIONS