Published April 2018 | Version v1
Journal article Metadata-only

Utilization of (p, 4n) reaction for 86Zr production with medium energy protons and development of a 86Zr → 86Y radionuclide generator

Creators

  • 1. Institute of Nuclear Physics, Almaty (Kazakhstan)
  • 2. DLNP, Joint Institute for Nuclear Research, Dubna (Russian Federation)
  • 3. Life Sciences Division, TRIUMF, Vancouver (Canada)
  • 4. Czech Technical University in Prague, Prague (Czech Republic). Department of Nuclear Chemistry
  • 5. Institute of Microelectronics Technology and High-Purity Materials, Chernogolovka (Russian Federation)
  • 6. Institute for Nuclear Research and Nuclear Energy, Sofia (Bulgaria)

Description

Utilization of (p, 4n) reaction channel for the production of medical radionuclides became very attractive with commercial availability of medium energy cyclotrons. Significantly higher yields and radionuclidic purity may open new perspectives for several novel and some of the radionuclides previously have not been considered due to production difficulties. In present work, we show the proof-of-principle study on the production of 86Y for Positron Emission Tomography imaging via radionuclide generator 86Zr → 86Y. Production suitability of 86Zr from natural yttrium target and radiochemical separation strategies were tested. In addition, two generator systems were proposed and evaluated. (author)

Additional details

Publishing Information

Journal Title
Journal of Radioanalytical and Nuclear Chemistry
Journal Volume
316
Journal Issue
1
Journal Page Range
p. 191-199
ISSN
0236-5731
CODEN
JRNCDM

INIS

Country of Publication
Hungary
Country of Input or Organization
Hungary
INIS RN
49052903
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CYCLOTRONS; IMPURITIES; ION EXCHANGE; ISOTOPE PRODUCTION; MEV RANGE 10-100; NUCLEAR MEDICINE; NUCLEAR REACTIONS; POSITRON COMPUTED TOMOGRAPHY; PROTONS; RADIOCHEMISTRY; RADIOISOTOPES; YTTRIUM 86; ZIRCONIUM 86
Descriptors DEC
ACCELERATORS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CHEMISTRY; COMPUTERIZED TOMOGRAPHY; CYCLIC ACCELERATORS; DIAGNOSTIC TECHNIQUES; ELECTRON CAPTURE RADIOISOTOPES; ELEMENTARY PARTICLES; EMISSION COMPUTED TOMOGRAPHY; ENERGY RANGE; EVEN-EVEN NUCLEI; FERMIONS; HADRONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MEV RANGE; MINUTES LIVING RADIOISOTOPES; NUCLEI; NUCLEONS; ODD-ODD NUCLEI; RADIOISOTOPES; TOMOGRAPHY; YTTRIUM ISOTOPES; ZIRCONIUM ISOTOPES

Optional Information

Notes
28 refs.